The seed of Hura crepitans could be described as a good food because it contained significant amount of essential nutrients required by man. The results revealed linoleic and oleic acids to be the most common in terms of abundance while palmitic acid was the least. The elemental composition of the seed showed Na, K, Ca and Mg in mg/100g to be 6.00 ± 0.01, 123.00 ± 0.02, 10.40 ± 0.03, 112.00 ± 0.01 respectively while other elements determined in mg/kg were Fe and Zn with 7.10 ☐.04 and 2.60± 0.01. We, therefore, present in this paper efforts to elucidate and bring to the fore the therapeutic potentials of Hura crepitans plant.Ī study in terms of proximate, elemental and fatty acid contents of (Hura crepitans) seed was investigated using standard analytical techniques. However much more biochemical studies need to be done to establish the hepatoprotective potentials of the various parts and various phytochemicals of Hura crepitans with the need for more preclinical and clinical studies. Their protective effects were enunciated using animal models. Four main phytochemicals were revealed to be contained in Hura crepitans stem-bark.
In achieving the above, intensive analyses of books and published peer-reviewed journal articles were carried out using credible scientific databases. The paper dwells extensively on the ethnomedical, phytochemical and pharmacological properties of the plant. This paper reviews the potential of the Hura crepitans plant in protecting the liver against drug-induced toxicity. JOCAMR, 9(2): 1-10, 2020 Article no.JOCAMR.55033 2 have also been documented. Toxicological, phytochemical and bactericidal studies Review Article Owojuyigbe et al. (Euphorbiaceae) or sandbox tree has been beneficial in many ethnomedicinal applications as a purgative, emetic, hepatoprotective, anti-inflammatory, antimicrobial and the treatment of leprosy. Secondary metabolites obtained from herbal sources contain bioactive phytochemicals, many of which have been the origin for the development of novel pharmaceutical drugs. Herbal medicines are the main source of treatment of diseases in non-urban centres of the developing world. crepitans seed is a nutritionally promising seed. This is followed by leucine, at 4.16 g/100 g of protein. Among the essential amino acids, arginine has the highest value (5.97 g/100 g of protein). crepitans seed is very rich in glutamate (14.41 g/100 g of protein) and deficient in cysteine (0.78 g/100 g of protein).
crepitans seed contains 328.1 IU of vitamin A/100 g, 0.398 mg of vitamin E/100 g, and 0.26 mg of vitamin K/100 g. A low peroxide value (6.6 +/- 0.2 mg/g) was observed in Hura oil. The iodine value of Hura oil was found to be 65.62 +/- 0.73%. The results also showed that the average molecular weight of glycerides is higher in the oil as reflected by the ester value (123.6 +/- 0.73 mg/g). The Hura oil has a high saponification value (127.16 +/- 0.18 mg/g) and low acid value (3.56 +/- 0.16 mg/g). crepitans oil contains 20.12% oleic acid, followed by stearic acid (3.0%), while linoleic acid is present at the lowest level (0.03%) among the other acids. crepitans seed also contains 1.85 ppm Na, 3.4 ppm K, 0.088 ppm Ca, and trace amounts of Mg, Fe, and Zn. The results of proximate analysis showed that H. Its trypsin inhibitor activity was found to be 30.27 +/- 1.86 TIU/mg of protein.
The results of antinutrient analysis showed that H. Antinutrient, proximate, mineral, fatty acid, vitamin, and amino acid analyses of sandbox tree (Hura crepitans) seeds were carried out.
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